I have rheumatoid arthritis for the last six years roughly. I take one shot a week of Actemra 0.9 ML I just turn 58 years old. I think in good health. I dont smoke drink about four times a year at parties. I been a realtor for 20 years. When I get tired from showing buildings I start running into walls, which is a good laugh. I can not do the tread mill because of the left side is my worst side. My right still going strong. My hands and feet hurt everyday but I am not in a wheelchair and I love to work. Please let me know if you need more info thks