Grant Projects


This page shows all of the active project grants that were awarded.

Lineage

Status Launched
Grant Date March 21, 2018
Github URL https://github.com/scedasticsoftware/lineage_app
Grantee Name Andrew Riha
Blog URL https://blog.openhumans.org/2018/03/23/meet-andrew-riha-our-next-project-grant-awardee/
Project Description lineage provides a framework for analyzing genotype (raw data) files from direct-to-consumer DNA testing companies (e.g., 23andMe, Family Tree DNA, and Ancestry), primarily for the purposes of genetic genealogy. Specifically, users can merge raw data files from different DNA testing companies (identifying discrepant SNPs in the process), compute centiMorgans (cMs) of shared DNA between individuals using the HapMap Phase II genetic map, plot shared DNA between individuals, determine genes shared between individuals (i.e., genes transcribed from shared DNA segments), find discordant SNPs between child and parent(s), and remap SNPs between assemblies / builds (e.g., convert SNPs from build 36 to build 37, etc.)

Imputer

Status Launched
Grant Date Feb. 9, 2018
Github URL https://github.com/arvkevi/open-humans-imputer/
Grantee Name Kevin Arvai
Blog URL https://blog.openhumans.org/2018/02/20/interviewing-project-grant-awardee-kevin-arvai/
Project Description The goal of Imputer is to provide users with a more comprehensive picture of their genome. Direct to consumer genetics companies, like 23andMe, only genotype a small fraction of the genome. Researchers are finding new genetic locations associated with traits and diseases at a rapid pace. Users might be interested in knowing their genotype status for these new associations, but the locations may be in regions that direct to consumer tests are not genotyping. Imputer leverages the vast amount of genotype data made available by 1000 genomes project to provide Open Humans users with genotype estimates at additional locations in their genome.